Post-Finasteride Syndrome: What You Need to Know

Are you considering taking finasteride (Propecia) for hair loss or an enlarged prostate? Before you do, it’s important to know about the possible side effects that could come with it. Post-finasteride syndrome (PFS) is very real, but it’s not widely talked about. Today, we’re changing that. 

As men’s health experts, we’ve seen how this drug can negatively impact men and women physically, mentally, and even sexually. From brain fog and weight gain to loss of libido and erectile dysfunction, PFS can cause a host of unwanted side effects. 

So, whether you’re already taking finasteride or thinking about starting it, here’s what you need to know about post-finasteride syndrome first. 

What is Finasteride Used For?

Finasteride is classified as a 5-alpha reductase type II enzyme inhibitor. For men, it’s primarily used to treat two common conditions: androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia (BPH), or an enlarged prostate.

These conditions might sound unrelated, but they can both be linked back to dihydrotestosterone (DHT), a hormone that plays a key role in how hair follicles and prostate tissue behave.

For hair loss, finasteride works by lowering DHT levels, finasteride can help slow down hair loss and, in some cases, even promote regrowth. On an episode of the Women Want Strong Men podcast, we spoke with Dr. Keith Nichols about DHT levels and hair loss. Check out this clip, then keep reading below for more on post-finasteride syndrome!

What to Consider

For men dealing with an enlarged prostate, finasteride can be an effective solution for reducing the size of the prostate gland and relieving symptoms like frequent urination, difficulty urinating, and a weak stream. In cases of benign prostatic hyperplasia (BPH), this medication can provide much-needed relief. 

However, for those considering finasteride primarily for hair loss, it’s important to carefully weigh the potential risks. Many men aren’t fully informed about the possible side effects, which can include impacts on mental health and sexual function. These are serious trade-offs to consider when balancing aesthetics with your overall well-being.

What is Post-Finasteride Syndrome?

Post-finasteride syndrome (PFS) describes a range of persistent sexual, neurological, physical, and mental side effects that can continue even after stopping the medication. Men who experience PFS often report that these adverse reactions linger long after they’ve discontinued finasteride—sometimes lasting for years.

For some men, PFS can be life-altering. The Post-Finasteride Syndrome Foundation has received reports from tens of thousands of men who have suffered from these long-term side effects. If you’re thinking about taking finasteride, it’s critical to be aware of the risks before starting the medication.

What are the Symptoms of Post-Finasteride Syndrome?

Post-finasteride syndrome (PFS) can impact every part of a man’s life. These side effects can be unexpected and difficult to manage, which is why it’s important to recognize the signs early on. Here’s a breakdown of the physical, sexual, and mental symptoms commonly associated with PFS.

Physical Symptoms:

• Muscle weakness and atrophy
• Chronic fatigue and low energy levels
• Joint pain and discomfort
• Weight gain or difficulty losing weight
• Dry skin or other skin issues

Sexual Symptoms:

• Loss of libido or reduced interest in sex
• Erectile dysfunction (ED) or difficulty maintaining an erection
• Reduced semen volume
• Decreased penile sensitivity
• Peyronie’s disease (development of scar tissue in the penis)

Mental/Neurological Symptoms:

• Depression, feelings of hopelessness, and suicidal ideation/behavior
• Anxiety and panic attacks
• Brain fog, difficulty concentrating, or memory issues
• Insomnia or sleep disturbances
• Dizziness or vertigo

Keep in mind: Not everyone who takes finasteride will develop PFS. We believe in empowering men to make informed choices about their health, which means understanding the potential risks you could be signing up for when you start a new medication. 

How Many Men Get PFS After Taking Finasteride?

It’s tough to know exactly how many men are affected by post-finasteride syndrome because not everyone realizes their symptoms could be linked to the medication, and many don’t report it to their doctors. Plus, the symptoms can vary widely and may not show up until long after stopping finasteride, making it harder to track.

However, research has helped to shed some light on the risks. A 2017 study published in PeerJ found the following: 

• 1.2% of young men (ages 16 to 42) who took finasteride for 206 days or longer, with no prior history of sexual dysfunction, developed persistent erectile dysfunction (PED) that lasted an average of 4.2 years after discontinuing the drug.
• Men who took finasteride for at least 205 days were nearly five times more likely to develop PED compared to men who used it for a shorter period.

To sum it up: The longer a man is on finasteride, the higher the risk of developing persistent sexual dysfunction.

How Long Does PFS Last? Is There a Cure?

Unfortunately, there’s currently no definitive cure for post-finasteride syndrome. Studies have observed that men can still experience symptoms for up to 16 months or longer after discontinuing the drug. In many cases, these side effects can persist for years, making PFS a long-term condition that’s difficult to treat.

While the medical community is beginning to recognize the scope of post-finasteride syndrome (PFS), effective treatments remain limited. If you think you might have PFS, we recommend seeking guidance from a healthcare provider experienced in men’s health.

A comprehensive hormone evaluation can shed light on potential ways to improve your symptoms and guide a tailored approach. At Victory Men’s Health, we understand the complexities of this condition and can work with you to explore possible solutions.

What Can I Take Instead of Finasteride?

If you’re looking for alternatives to finasteride, there are plenty of natural ingredients known to be effective for both hair loss and prostate health. For example, saw palmetto has been widely studied for its ability to block DHT, the hormone linked to both hair loss and prostate enlargement. 

Other ingredients like beta-sitosterol and pygeum have been shown to support urinary function and reduce prostate symptoms, while biotin and pumpkin seed oil are often recommended for promoting healthy hair growth. 

In addition to natural options, there are alternative medications that may offer benefits with fewer side effects. For hair loss, minoxidil and topical versions of finasteride or dutasteride reduce systemic side effects. 

Treatments like PRP, hair transplants, and red light therapy, when supervised by a hair loss specialist, can also be effective approaches. For prostate health, daily tadalafil (Cialis) is FDA-approved for managing BPH and offers the added benefits of improving erectile function and overall blood flow.

What Can I Take for Hair and Prostate Health?

At Victory Men’s Health, we’re proud to offer products that are formulated with clinically proven ingredients to help men maintain their hair and support prostate health safely and effectively. Here are two of our top recommendations:

• Hair Science Formula 82S: This 2-in-1 shampoo and conditioner is designed to help prevent hair loss and strengthen hair fibers using natural ingredients like saw palmetto. It’s a safe, effective alternative to finasteride, providing benefits like improved hair texture and stronger hair growth, thanks to its blend of natural extracts, vitamins, and amino acids.

• Prostate Support: Our unique prostate formula combines saw palmetto, beta-sitosterol, pygeum, and FLOWENS® full-spectrum cranberry powder. These ingredients work together to support urinary function and overall prostate health. If you’re experiencing mild urinary concerns and aren’t currently on medications, this supplement could be a good choice. However, it’s not a replacement for medication. If you’re already on finasteride for urological reasons and have concerns about side effects, speak with your provider about alternative options in other medication classes.

If you’re looking for ways to support your hair and prostate health without the potential side effects of finasteride, our team is here to guide you in choosing the best and safest options for your needs.

Take Control of Your Health—Without Compromising Safety

Post-finasteride syndrome is a serious condition that too many men are unaware of, but we’ve seen its frustrating effects firsthand. From sexual dysfunction to mental health challenges, PFS can have a lasting impact on your life. The good news is that there are alternatives to finasteride that can help you achieve your health goals without the same risk.
If you’re struggling with hair loss or an enlarged prostate and want to explore safe, effective treatment options, we’re here to help. Reach out to book a consultation with our team in one of our clinics in Illinois or Missouri. Let’s help you find a solution to your health concerns without the potential side effects of finasteride.