NAD: Side Effects & Benefits No One Is Talking About

If you’re tuned into the latest health and wellness trends, you’ve probably heard about NAD. Nicotinamide Adenine Dinucleotide (NAD) is making waves as a powerful supplement for boosting energy, slowing the visible signs of aging, and enhancing overall vitality. 

But what really sets NAD apart isn’t just its headline-worthy benefits—it’s the lesser-known perks and potential side effects that make it such an intriguing topic for medical professionals.

We’re diving into everything you need to know, including the NAD side effects and benefits that no one seems to be talking about. Whether you’re thinking of adding this supplement to your daily regimen or just want to learn what all the fuss is about, you’ve come to the right place. 

What Is Nicotinamide Adenine Dinucleotide (NAD)?

NAD is a molecule found in every cell of your body that acts like a battery, powering essential processes that keep you alive and healthy.

To better understand it, start by thinking of it as the key to your body’s power supply. NAD plays a crucial role in cellular energy production and metabolic health. Every cell in your body relies on NAD to function properly, as it’s directly involved in energy metabolism and DNA repair.

Your body naturally produces NAD through several biochemical pathways. It’s primarily synthesized from vitamin B3 precursors and the amino acid tryptophan. However, as you age, NAD levels decline, which can contribute to fatigue, cognitive decline, and signs of aging.

Nicotinamide Riboside (NR) is a precursor to NAD, meaning it helps your body naturally produce more of it. Because lower NAD levels can impact energy, focus, and overall vitality, supplementing with NR (often marketed as NAD for ease) can support cellular health and help you feel more energized and resilient.

If you’ve ever wondered why your energy levels aren’t what they used to be, declining NAD might be part of the puzzle—and supplementation could be the solution.

How Does NAD Work in the Body?

This molecule works behind the scenes, supporting some of your body’s most essential processes. At its core, NAD is involved in mitochondrial function, which is key to energy production. Mitochondria are often referred to as the “powerhouses” of our cells, and NAD ensures they run efficiently.

Beyond energy, NAD plays a major role in DNA repair. Every day, your DNA sustains damage from environmental factors like UV exposure, pollution, and stress. NAD helps repair this damage, contributing to healthier aging and reduced risk of disease. 

Want to learn more about environmental toxins and their effects on the body? Check out the video below, then keep reading for more on Nicotinamide Adenine Dinucleotide. 

Additionally, NAD reduces oxidative stress, a process that accelerates aging and damages cells. By fighting oxidative stress, it helps maintain cellular health and resilience. In short, it’s basically your body’s ultimate multitasker—tackling everything from energy metabolism to anti-aging and cellular repair.

NAD Benefits No One Talks About

You’ve likely heard about NAD’s ability to boost energy and combat the signs of aging, but there’s more to the story. Here are some lesser-known benefits that deserve the spotlight:

• Enhanced Brain Function – NAD supports neurons and brain cell repair, potentially improving memory, focus, and mental clarity.

• Cardiovascular Support – NAD may play a role in improving blood vessel function and reducing inflammation, which supports heart health.

• Metabolic Health – Emerging research suggests NAD supplementation could help with insulin sensitivity and managing metabolic syndrome.

• Stress and Fatigue Resilience – By boosting cellular energy, NAD can enhance your body’s ability to recover from stress and fatigue more effectively.

While the anti-aging and energy-boosting benefits tend to grab headlines, these additional perks make NAD a comprehensive health booster. If you’re interested in taking a holistic approach to your well-being, this is the kind of powerhouse supplement worth knowing about. 

What are the Side Effects of NAD?

As promising as NAD sounds, everything in life has its potential drawbacks. The good news? For most people, any side effects are mild and temporary. However, it’s important to note that the following side effects are possible when you supplement with NAD: 

• Nausea or digestive discomfort
• Flushing or warmth
• Rare allergic reactions

To minimize the risk of experiencing side effects, it’s best to start with a lower dose and gradually increase it under the guidance of a healthcare provider. You can minimize flushing by staying hydrated and reduce stomach discomfort by taking NAD with food. 

If you’re concerned about possible side effects of NAD, consult with your healthcare provider to determine the best approach for your needs and goals. 

Who Should Consider NAD Supplements?

Not sure if NAD is right for you? Here’s who stands to benefit most:

• Individuals Experiencing Low Energy or Fatigue: If you’re constantly feeling drained, this tool might help recharge your batteries.
• Those Looking to Improve Cognitive Function: Whether you’re noticing signs of aging or just want sharper focus, NAD can support brain health.
• Athletes or Active Individuals: This supplement may enhance recovery, giving you an edge in your fitness routine.
• People with Metabolic Concerns: If you’re managing insulin resistance or metabolic syndrome, NAD could support your efforts.

As with any supplement, it’s important to consult with a healthcare provider before starting NAD, especially if you have underlying health conditions.

How to Take NAD Supplements

We currently offer NAD+ injections as an at-home treatment with subcutaneous injections and Niagen infusions in-office. We do not yet carry oral options in-office, but we can discuss oral versions of therapy with you. Our Niagen IV infusions come in three dosing options: 100mg, 200mg, and 500mg. 

If it’s a viable option for you, we recommend coming in for the Niagen IV option, as it enhances NAD levels efficiency with a quicker and more tolerable infusion time (30-60 minutes) compared to standard NAD+ infusions, which can take up to 4 hours.

Ready to add NAD to your wellness routine? Here’s what to know first: 

• Dosage: Dosing depends on your specific needs, but many oral supplements for NAD (like TruNiagen) start at 300mg daily, with high-dose options up to 1000mg.

• Administration: We offer Niagen+ IV, an NAD precursor, in our clinic. You can also take NAD+ via subcutaneous injections or oral supplementation (NR or NMN) at home. 

• Cost: TruNiagen oral supplements start at $50/month for 300mg or $116/month for 1,000mg. Niagen IV infusions range from $219 to $650 per session, depending on the dose. 

• With Food or Empty Stomach: While NAD can be taken on an empty stomach, taking it with food may help reduce digestive discomfort.

• Pairing with Other Supplements: Some people choose to combine NAD with CoQ10, glutathione, or resveratrol for enhanced anti-aging benefits, under the guidance of a physician. 

• Work with a Provider: Before making any changes to your current supplement regimen, always consult with your healthcare provider to ensure it’s a good fit. Your provider can also provide guidance on the best dosage and time of day to take it. 

Questions Our Patients Ask About NAD

What does NAD do for your body?

NAD is a crucial molecule that supports your body’s energy production, helps repair damaged DNA, and plays a key role in maintaining healthy metabolism. It ensures your cells function optimally, which impacts everything from energy levels to how well your body ages.

How quickly will I notice results?

While individual results vary, many people report feeling more energized, focused, and mentally clear within a few weeks of starting supplementation. Factors like your starting levels, overall health, dosage, and consistency can influence how quickly you experience benefits.

Is NAD safe for long-term use?

Absolutely! NAD is considered safe for long-term use when taken as directed. Regular consultations with your healthcare provider allow them to monitor your progress and make adjustments as needed to ensure it’s both effective and aligned with your health goals.

Can NAD improve sleep or mood?

Yes, NAD can improve sleep and mood by enhancing cellular repair and resilience to stress. Many patients report experiencing more restful sleep and better emotional balance, thanks to its ability to support brain health and reduce oxidative stress.

Are there natural ways to boost NAD levels?

Of course! Engaging in regular physical activity, practicing intermittent fasting, and eating a diet rich in healthy fats (such as avocados and nuts) can help naturally boost your NAD levels. Pairing these habits with NAD supplementation can amplify your results for an even more significant health boost.

Boost Your Energy, Brainpower, and Longevity Today

NAD is a powerful tool for improving energy, cognitive function, and longevity. From its lesser-known benefits to its mild side effects, understanding more about this supplement can help you make an informed decision about whether it’s right for you.

At Victory Men’s Health, we offer NAD+ in multiple forms, including IV infusions and at-home injections. Whether you’re looking to boost energy, build muscle, lose weight, or explore ED solutions, our team is here to help. 

Ready to take control of your health? Contact us today to book a consultation and begin your journey toward a stronger, healthier, and happier you.